Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314406 | Journal of Fluorine Chemistry | 2011 | 4 Pages |
Abstract
Addition of both alkyl phosphites and phosphonate α-carbanions to N-substituted aldimines derived from fluoroalkyl aldehydes presents a convenient method for synthesis of fluoroalkyl α- and β-aminophosphonates in good yield (55–86%) under mild conditions.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Procedure for the preparation of fluoroalkyl α- and β-aminophosphonic acid derivatives. ► Addition of alkylphosphites and phosphonate α-carbanions to N-substituted fluoroalkyl aldimines under mild conditions. ► Substituents on the nitrogen can be removed using standard methods.
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Gerd-Volker Röschenthaler, Valery P. Kukhar, Irene B. Kulik, Alexander E. Sorochinsky, Vadim A. Soloshonok,