Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314479 | Journal of Fluorine Chemistry | 2013 | 17 Pages |
A variety of trifluoromethylated bi- and terphenyls were prepared by site-selective Suzuki–Miyaura cross-coupling reactions of various dihalogenated trifluoromethyl-substituted benzene derivatives. The reactions proceed with excellent site-selectivities.
Graphical abstractA variety of trifluoromethylated di- and terphenyls were prepared by site-selective Suzuki–Miyaura cross-coupling reactions of various dihalogenated trifluoromethyl-substituted benzene derivatives. The reactions proceed with excellent site-selectivities.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► A variety of CF3-substituted benzene derivatives were prepared. ► The reactions proceed with very good site-selectivity. ► The selectivity is controlled by steric and electronic parameters. ► The reactions proceed in good yields.