Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314518 | Journal of Fluorine Chemistry | 2008 | 6 Pages |
Abstract
A facile one-pot method has been developed for the synthesis of fluorine-containing propargylamines by a three-component coupling of fluorinated aldehydes, amines, and alkynes, in the presence of copper (I) chloride under microwave irradiation and solvent-free condition. This process is an efficient alternative to traditional thermal reaction. All new compounds are fully characterized by spectral methods.
Graphical abstractA facile one-pot method has been developed for this A3 coupling reaction to gain series new fluorinated propargylamines under microwave irradiation and solvent-free condition.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Wei-Qiong Du, Jian-Min Zhang, Ran Wu, Qin Liang, Shi-Zheng Zhu,