Article ID Journal Published Year Pages File Type
1314518 Journal of Fluorine Chemistry 2008 6 Pages PDF
Abstract

A facile one-pot method has been developed for the synthesis of fluorine-containing propargylamines by a three-component coupling of fluorinated aldehydes, amines, and alkynes, in the presence of copper (I) chloride under microwave irradiation and solvent-free condition. This process is an efficient alternative to traditional thermal reaction. All new compounds are fully characterized by spectral methods.

Graphical abstractA facile one-pot method has been developed for this A3 coupling reaction to gain series new fluorinated propargylamines under microwave irradiation and solvent-free condition.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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