| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314543 | Journal of Fluorine Chemistry | 2010 | 8 Pages |
Trifluoromethylation of aromatic and hetero-aromatic compounds by CF3I in the presence of Fe(II) compound, H2O2 and dimethylsulfoxide was investigated. Various trifluoromethylated benzene derivatives, six-membered nitrogen-containing aromatic compounds and five-membered hetero-aromatic compounds were obtained under mild conditions. General orientation of electrophilic substitution of aromatic compounds was observed similarly as reported in other radical trifluoromethylation previously.
Graphical abstractTrifluoromethylation of aromatic compounds by CF3I in the presence of Fe(II) compound, H2O2 and dimethylsulfoxide was investigated. General orientation of electrophilic substitution of aromatic compounds was observed.Figure optionsDownload full-size imageDownload as PowerPoint slide
