| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314576 | Journal of Fluorine Chemistry | 2011 | 4 Pages |
As a kind of organocatalyst, 1-[4-(perfluorooctyl)phenyl]-3-phenylthiourea was employed to the chemoselective oxidation of sulfides in the presence of 30% H2O2. A variety of diaryl, dialkyl, alkyl aryl sulfides could be oxidized to sulfoxide under the mild condition. The catalyst could be easily recovered by fluorous solid-phase extraction for reuse.
Graphical abstractAs a kind of organocatalyst, 1-[4-(perfluorooctyl)phenyl]-3-phenylthiourea was employed to the chemoselective oxidation of sulfides in the presence of 30% H2O2. A variety of diaryl, dialkyl, alkyl aryl sulfides could be oxidized to sulfoxide under the mild condition. The catalyst could be easily recovered by fluorous solid-phase extraction for reuse.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► The sulfoxides could be oxidized selectively in moderate to good yields under the mild condition. ► The oxidative system of 30% H2O2 was more eco-friendly than other metal-based oxidative systems. ► Organocatalytic system based on thiourea derivative is of low cost and low toxicity compared with some traditional metal-based catalysts. ► Fluorous thiourea-based organocatalyst could be easily separated from the reaction mixtures by fluorous solid phase extraction for direct reuse.
