Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314606 | Journal of Fluorine Chemistry | 2008 | 6 Pages |
Abstract
When 4-nitro-AF4 is treated with nucleophiles such as alkoxides and cyanide, a novel ring opening, cyclophane destroying reaction is observed whereby, via an SNAr mechanism, the nucleophile attacks the bridgehead aryl carbon vicinal to the nitro group with subsequent aryl-CF2 bond cleavage.
Graphical abstractNucleophilic ring opening reactions of 4-nitro-AF4 are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
William R. Dolbier Jr., Yian Zhai, Wei Xu, Will Wheelus, Florian Dulong, Efram Goldberg, Ion Ghiviriga, Merle A. Battiste,