| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314606 | Journal of Fluorine Chemistry | 2008 | 6 Pages |
Abstract
When 4-nitro-AF4 is treated with nucleophiles such as alkoxides and cyanide, a novel ring opening, cyclophane destroying reaction is observed whereby, via an SNAr mechanism, the nucleophile attacks the bridgehead aryl carbon vicinal to the nitro group with subsequent aryl-CF2 bond cleavage.
Graphical abstractNucleophilic ring opening reactions of 4-nitro-AF4 are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
![Novel ring-cleaving reaction of 4-nitro-1,1,2,2,9,9,10,10-octafluoro[2.2]paracyclophane with nucleophiles](/preview/png/1314606.png "First Page Preview: Novel ring-cleaving reaction of 4-nitro-1,1,2,2,9,9,10,10-octafluoro[2.2]paracyclophane with nucleophiles")
Authors
William R. Dolbier Jr., Yian Zhai, Wei Xu, Will Wheelus, Florian Dulong, Efram Goldberg, Ion Ghiviriga, Merle A. Battiste,