Palladium catalyzed the Suzuki cross-coupling reaction using a fluorous NHC ligand

The utilization of N-heterocyclic carbene palladium complex immobilized on fluorous silica gel through fluorous–fluorous interactions in the Suzuki cross-coupling reaction was described. The reactions were carried out under aerobic and phosphine-free conditions with moderate to excellent product yields. The catalyst was easily recovered and reused three times without significant loss of activity.

Graphical abstract. The utilization of N-heterocyclic carbene palladium complex immobilized on fluorous silica gel through fluorous–fluorous interactions in the Suzuki cross-coupling reaction was described. The catalyst was easily recovered and reused three times without significant loss of activity.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► A novel fluorous NHC–Pd catalyst prepared by fluorous–fluorous interactions. ► Suzuki reactions were carried out under phosphine-free condition. ► The catalyst could be reused three times without significant loss of activity.