Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314685 | Journal of Fluorine Chemistry | 2008 | 5 Pages |
Abstract
Fourteen novel 3-substituted-5-methyl-4-methylene-7-alkylsulfanyl-3,4-dihydro-pyrido[4,3-d]pyrimidine-8-carbonitriles 4a-n were synthesized via a facile regioselective cyclization process. The structures of compounds 4a-n were confirmed by IR, 1H NMR, MS and elemental analysis. Some compounds possess good herbicidal activity, especially when the fluorine atom was introduced to the para position of substituents on pyrimidine ring. And some compounds show moderate fungicidal activities as well, and the introduction of fluorine has negative effect on the antifungal activities.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Wenyan Mo, Guihong Liao, Tao Wang, Hongwu He,