Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314728 | Journal of Fluorine Chemistry | 2012 | 5 Pages |
Abstract
A highly efficient cyclization reaction of trifluoromethylated propargylamines leading to 2-trifluoromethyl-4-aryl quinolines was developed by using gold(I) as a catalyst under extremely mild conditions.
Graphical abstractA highly efficient cyclization reaction of trifluoromethylated propargylamines leading to 2-trifluoromethyl-4-aryl quinolines was developed by using gold(I) as a catalyst under extremely mild conditions.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Gold-catalyzed cyclization of trifluoromethylated propargylamines. ► Various 1-trifluoromethylpropargylamines are viable substrates. ► The reaction mechanism is suggested to involve cyclization-oxidation.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Mei Zhu, Weijun Fu, Guanglong Zou, Chen Xun, Dongsheng Deng, Baoming Ji,