Article ID Journal Published Year Pages File Type
1314728 Journal of Fluorine Chemistry 2012 5 Pages PDF
Abstract

A highly efficient cyclization reaction of trifluoromethylated propargylamines leading to 2-trifluoromethyl-4-aryl quinolines was developed by using gold(I) as a catalyst under extremely mild conditions.

Graphical abstractA highly efficient cyclization reaction of trifluoromethylated propargylamines leading to 2-trifluoromethyl-4-aryl quinolines was developed by using gold(I) as a catalyst under extremely mild conditions.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Gold-catalyzed cyclization of trifluoromethylated propargylamines. ► Various 1-trifluoromethylpropargylamines are viable substrates. ► The reaction mechanism is suggested to involve cyclization-oxidation.

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Authors
, , , , , ,