| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1314799 | Journal of Fluorine Chemistry | 2007 | 5 Pages |
Abstract
The 1,3-dipolar cycloaddition reaction of fluoro(trimethylsilyl)acetylene prepared in situ with an excess of diazomethane smoothly proceeded to give the corresponding 4-fluoro-5-trimethylsilyl-1H-pyrazole in 84% yield. The copper iodide-catalyzed N-arylation of the fluorinated pyrazole with a variety of aryl iodides afforded N-aryl-4-fluoropyrazoles as desilylation products in good to excellent yields.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Takeshi Hanamoto, Yuhko Iwamoto, Kenji Yamada, Ryoko Anno,