Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314811 | Journal of Fluorine Chemistry | 2007 | 5 Pages |
Abstract
A short series of bromo- and nitro-polyfluorobenzene derivatives gave the corresponding tetrahydroquinoxaline systems upon reaction with N,N′-dimethylethylene diamine. This annelation strategy gives useful quantities of functionalised tetrahydroquinoxaline systems which may be interesting scaffolds for the drug discovery arena.
Graphical abstractPolyfluorobenzene derivatives gave tetrahydroquinoxaline systems upon reaction with N,N′-dimethylethylene diamine.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Graham Sandford, Andrzej Tadeusiak, Dmitrii S. Yufit, Judith A.K. Howard,