Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1314837 | Journal of Fluorine Chemistry | 2008 | 11 Pages |
Abstract
The synthesis of N-(2-trifluoroacetylaryl)propargylamines 10-14 and 17 is presented. The copper(I) catalyzed cycloaddition reaction of these propargylamines (dipolarophiles) with a series of azides (1,3-dipoles) 18-20, 21 and 24 was found to proceed smoothly in dimethylsulfoxide at room temperature, to furnish the corresponding 1,4-disubstituted-[1,2,3]triazole derivatives 26-36 in moderate to good yields.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Jean-Florent Lamarque, Christophe Lamarque, Sandrine Lassara, Maurice Médebielle, Jérome Molette, Emilie David, Stéphane Pellet-Rostaing, Marc Lemaire, Etsuji Okada, Dai Shibata, Guillaume Pilet,