Article ID Journal Published Year Pages File Type
1314867 Journal of Fluorine Chemistry 2010 5 Pages PDF
Abstract

S(−)-4-Aryl-4-(N-acylamino)-5,5,5-trifluoropentan-2-ones have been reacted with phosphorus pentachloride and pentasulfide to yield S(−)-4-aryl-4-trifluoromethyl-4H-1,3-oxazines and S(+)-4-aryl-4-trifluoromethyl-4H-1,3-thiazines, respectively.

Graphical abstractSynthesis of chiral 4-trifluoromethyl-4H-1,3-oxazines and 4-trifluoromethyl-4H-1,3-thiazines from enantiomerically enriched N-acyl derivatives of 4-amino-4-aryl-5,5,5-trifluoropentan-2-ones is described.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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