19F NMR of linear N,N-difluoroaminoalkanes

Whereas most N,N-difluoroaminoalkanes exhibit a single 19F resonance at about +50 ppm, the tri-component mixtures of both N,N-difluoroaminopentanes and N,N-difluoroaminohexanes exhibited a more complex pattern. The individual 1-N,N-difluoroamino-, 2-N,N-difluoroamino- and 3-N,N-difluoroaminopentanes have been synthesized and their separated resonances are reported.

Graphical abstract19F NMR of difluoroaminoalkanes.Figure optionsDownload full-size imageDownload as PowerPoint slideHighlight► 19F NMR resonances for 1-, 2- and 3-difluoroaminoalkanes have been differentiated. ► 1-difluoroaminopentane and 1-difluoroaminohexane exhibit a single resonance at δ +55.8 ppm. ► 3-difluoroaminopentane and 3-difluoroaminohexane exhibit a single resonance at δ +39.4 ppm. ► 2-difluoroaminopentane and 2-difluoroaminohexane each exhibit two resonances at δ +35.7 (d, J = 565.7 Hz), +43.1 (d, J = 565.7 Hz).