| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1315106 | Journal of Fluorine Chemistry | 2007 | 4 Pages |
Abstract
A series of fluorinated galactosides, dodecyl 2-deoxy-2-fluoro-β-d-galactopyranoside (2F Gal), dodecyl 4-deoxy-4-fluoro-β-d-galactopyranoside (4F Gal) and dodecyl 6-deoxy-6-fluoro-β-d-galactopyranoside (6F Gal), was chemically synthesized and introduced to B16 cells to serve as scaffolds for cellular enzyme glycosylation. Results showed that the presence of fluorine exercised significant effects on cell viability. Among the fluorinated galactosides used, 2F Gal was glycosylated to afford a GM4 analogue.
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Maria Carmelita Kasuya, Ayaka Ito, Kenichi Hatanaka,