Article ID Journal Published Year Pages File Type
1315191 Journal of Fluorine Chemistry 2009 5 Pages PDF
Abstract

The aldol reactions of amide enolates derived from a trifluoromethylated oxazolidine (Fox) chiral auxiliary occur in good yields with a moderate anti diastereoselectivity (Li and Na enolates) to a high syn diastereoselectivity (boron enolate). After removal, the Fox chiral auxiliary is very conveniently and efficiently recovered in basic conditions.

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Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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