| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1315193 | Journal of Fluorine Chemistry | 2009 | 6 Pages |
Abstract
We have validated a novel detagging strategy featuring the unmasking of a fluorous-tagged silane to a hydroxy moiety. The fluorous silylated bicyclononane, prepared from the titanium-mediated annulation of 1-acetylcyclohexene and a fluorous-tagged allylsilane, was successfully detagged under Fleming-type oxidation conditions. The stereochemistry of the resulting hydroxylated product indicates retention of configuration upon detagging in line with the non-fluorous variant of this transformation.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Sophie Boldon, Jane E. Moore, Véronique Gouverneur,