Synthesis and characterisation of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives: X-ray structure of 3–SF5–C6H4–COOH

The high yield synthesis of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives is described starting from the NO2-derivatives, which are reduced to the corresponding anilines. Then the NH2– group is converted to bromide and subsequently to the HCO moiety. The benzaldeydes are then oxidised to the corresponding benzoic acids. The X-ray structure of 3–SF5–C6H4–COOH is also reported.

Graphical abstractHigh yields of 3- and 4-(pentafluorosulfanyl)benzoic acids are obtained through four step syntheses starting from the corresponding nitro-(pentafluorosulfanyl)benzene derivatives.Figure optionsDownload full-size imageDownload as PowerPoint slide