| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1315217 | Journal of Fluorine Chemistry | 2006 | 6 Pages |
Fluorine presents among its radioactive isotopes fluorine-18, that decays with a 109 min half-life and a β+ emission, allowing external detection of the two coincident γ photons obtained after annihilation. Production techniques (medical cyclotron), radiochemical reactions for isotope incorporation in radiopharmaceuticals and development of specific detection cameras (positron emission tomographs) allowed development of a vast investigation field in medical imaging.Applications of PET in oncology ([18F]fluorodeoxyglucose, FDG) largely improved detection and management of cancers; tracer molecules labelled with fluorine-18 also allow fruitful researches in molecular imaging.
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