Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315308 | Journal of Fluorine Chemistry | 2006 | 11 Pages |
Abstract
Three-component Grieco condensation reaction of 3-aminopyrazolo[3,4-b]pyridine, formaldehyde/benzaldehyde and electron rich alkenes in presence of iron(III) chloride gave tetrahydropyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidines/quinazolines in single pot. The sequence of reactions is formation of di-azadiene in situ and the subsequent regioselective addition of alkenes in aza-Diels Alder type reaction. The structure and stereochemistry of the products were confirmed by spectral data and single crystal X-ray crystallography.
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
S. Ravi Kanth, G. Venkat Reddy, D. Maitraie, B. Narsaiah, P. Shanthan Rao, K. Ravi Kumar, B. Sridhar,