Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315512 | Journal of Fluorine Chemistry | 2009 | 4 Pages |
Abstract
The catalytic enantioselective electrophilic α-hydrazination promoted by chiral nickel complexes is described. Treatment of α-fluoro-β-ketoesters with azodicarboxylates as electrophilic amination reagents under mild reaction conditions afforded the corresponding α-amino α-fluoro-β-ketoesters with high yields (80–96%) and enantioselectivities (up to 78% ee).
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Joo Yang Mang, Dae Gil Kwon, Dae Young Kim,