Article ID Journal Published Year Pages File Type
1315512 Journal of Fluorine Chemistry 2009 4 Pages PDF
Abstract

The catalytic enantioselective electrophilic α-hydrazination promoted by chiral nickel complexes is described. Treatment of α-fluoro-β-ketoesters with azodicarboxylates as electrophilic amination reagents under mild reaction conditions afforded the corresponding α-amino α-fluoro-β-ketoesters with high yields (80–96%) and enantioselectivities (up to 78% ee).

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Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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