Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315608 | Journal of Fluorine Chemistry | 2007 | 4 Pages |
Abstract
The title fluorodiene (2) reacts with several dienophiles in moderate yields (20–65%, 0.5 h to 3d) when thermal activation is used. When 100 W microwave radiation is used the reaction yields (70–90%, 5–25 min) are greatly improved and the reaction times are much shorter. A microwave procedure is also used for the hydrolysis of vinyl ether cycloadducts to alpha-fluoroketones.
Graphical abstractThe title compound, 2, undergoes Diels-Alder cyclization with a number of dienophiles. The reactions occur in moderate yield thermally, but occur in very good yield with microwave radiation. Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Timothy B. Patrick, Keith Gorrell, James Rogers,