Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315681 | Journal of Fluorine Chemistry | 2006 | 6 Pages |
Abstract
A strong DNA cleavage property switched by photo irradiation was found for 9-anthracenecarboxylic acid substituted gem-difluorocyclopropane derivatives; in particular, a clear contrast in the activity was observed between the enantiomers of (S,S)- and (R,R)-3-aminomethyl-2,2-difluorocyclopropylmethyl 9-anthracenecarboxylate.
Graphical abstractA unique DNA cleavage property switched by photo irradiation was found for anthracene–cyclopropane hybrids compounds. Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Keiko Ninomiya, Kunihiko Tanimoto, Nanae Ishida, Daisuke Horii, Masahiko Sisido, Toshiyuki Itoh,