Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315693 | Journal of Fluorine Chemistry | 2006 | 5 Pages |
Abstract
This paper describes an efficient, practical synthesis of 3,5-bis(trifluoromethyl)benzylamine via biomimetic transamination of 3,5-bis(trifluoromethyl)benzaldehyde with benzylamine. From a synthetic standpoint the reported procedure is highly operationally convenient and scalable as it does not require any chromatographic purification of the intermediate products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Vadim A. Soloshonok, Manabu Yasumoto,