Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1315718 | Journal of Fluorine Chemistry | 2006 | 9 Pages |
Abstract
Two strategies have been developed for the synthesis of novel quinazoline derivatives. 2,6-Dicyanoanilines were reacted with Grignard reagents followed by cyclization to give two quinazoline regioisomers 2 and 3. Alternately 2,6-dicyanoanilines on reaction with Grignard reagents gave imine regioisomers 4 and 5. Each imine regioisomer was separated and independently cyclized to give new quinazoline derivatives 6, 7 and 8, 9, respectively, under different microwave irradiation conditions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
D. Maitraie, T. Yakaiah, K. Srinivas, G. Venkat Reddy, S. Ravikanth, B. Narsaiah, P. Shanthan Rao, K. Ravikumar, B. Sridhar,