Facile synthesis of fluorinated α-imino alkynes by the coupling reaction of imidoyl iodides with terminal alkynes

A series of N-arylbromodifluoroacetimidoyl iodides and 1-alkynes were converted into α-imino alkynes by using Pd(Ph3)2Cl2/CuI as the catalyst under mild conditions. The reaction proceeded smoothly to give the coupling products in good to excellent yields.

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