Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1316142 | Journal of Inorganic Biochemistry | 2011 | 7 Pages |
Abstract
A spectroscopic analysis shows that the B10Phe residue is essential to translate the formation of the internal disulfide bridge in human neuroglobin in a strong change of the heme-pocket conformation and that mutation of this residue leads to a reduced protein stability in the presence of H2O2.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Maria Ezhevskaya, Florin Trandafir, Luc Moens, Sylvia Dewilde, Sabine Van Doorslaer,