In vivo potential antidiabetic activity of a novel zinc coordination compound based on 3-carboxy-pyrazole

A novel Zn mononuclear complex with 3-carboxy-pyrazole ligand has been prepared using conventional routes and characterized by X-ray diffraction. The structure consists of discrete neutral [Zn(C6H3N2O2)2(H2O)2] molecules held together by hydrogen interactions. This compound exhibits a potential in vivo antidiabetic activity and the in vitro toxicity can be considered negligible.

Graphical abstractA novel Zn mononuclear complex with 3-carboxy-pyrazole ligand has been prepared using conventional routes and characterized by X-Ray diffraction. The structure consists of discrete neutral [Zn(C4H3N2O2)2(H2O)2] molecules held together by hydrogen interactions. This compound exhibits a potential in vivo antidiabetic activity. Moreover, we have evaluated the in vitro toxicity concluding that it can be considered negligible.Figure optionsDownload full-size imageDownload as PowerPoint slide