| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1317050 | Journal of Inorganic Biochemistry | 2011 | 5 Pages |
Abstract
The platinum(II) complex of 3,6-diamine-9-[6,6-bis(2-aminohethyl)-1,6-diaminohexyl]acridine (AzaPt) is synthesised and found to bind DNA externally or by intercalation, depending on the polymer to dye ratio; in the long time range the Pt(II) ion is able to attack the nucleobases, in a manner resembling the action of anti-tumour drugs.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Silvia Biagini, Antonio Bianchi, Tarita Biver, Alessia Boggioni, Igor V. Nikolayenko, Fernando Secco, Marcella Venturini,