Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1317407 | Journal of Inorganic Biochemistry | 2006 | 10 Pages |
Abstract
Many properties of cytochromes and model systems depend on orientations of axial ligands. In this work, we elucidated the role of porphyrin substituents on orientation of axial ligands in model systems of cytochromes. The orientations of axially coordinated imidazoles and pyridines in crystal structures of model systems of cytochromes were analyzed and data were compared with previous quantum-chemical calculations. The results show that eight ethyl groups on porphyrin ring strongly favor parallel orientation, hence, in all these complexes axial ligands, pyridines or imidazoles, are mutually parallel. Four phenyl or mesityl groups at meso-carbons also favor parallel orientation but less strongly. Hence, in most of the bis-imidazole complexes the orientation is parallel, while in bis-pyridine complexes the orientation of pyridines depends on oxidation state of Fe. In bis-pyridine Fe(II) complexes orientation is parallel, in Fe(III) it is orthogonal. This analysis is in agreement with previous quantum-chemical calculations.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Aleksandra A. RakiÄ, Vesna B. MedakoviÄ, Snežana D. ZariÄ,