| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1317552 | Journal of Inorganic Biochemistry | 2013 | 10 Pages |
Abstract
Indolone-N-oxides (INODs) generate radical intermediates by reduction which may initiate a fatal redox signal within parasitized erythrocytes. This reaction is not iron-dependent. INODs present physico- and bio-chemical properties which are different of those of existing antimalarial drugs to which the parasite has become resistant.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Nguyen Thi Hoang Yen, Hany Ibrahim, Karine Reybier, Pierre Perio, Florence Souard, Ennaji Najahi, Paul-Louis Fabre, Francoise Nepveu,