Article ID Journal Published Year Pages File Type
1317898 Journal of Inorganic Biochemistry 2011 8 Pages PDF
Abstract
Three cobalt complexes [CoII(L1)2] (1), [CoII(L2)] (2), and [CoIII(L1)2]ClO4 (3) were synthesized, characterized, and evaluated as potential agents for 26S proteasome inhibition in PC-3 cancer cells. Effects of ligand tethering and metal oxidation state are discussed.
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Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
Effects of tethered ligands and of metal oxidation state on the interactions of cobalt complexes with the 26S proteasome
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