| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1322220 | Journal of Organometallic Chemistry | 2015 | 6 Pages |
Abstract
•Amidation of alkenes with nitriles that avoids the use of strong Bronsted acid.•A novel NbCl5-mediated transformation to secondary amides.•A practical route to amides from simple alkenes and nitriles.
NbCl5-mediated amidation of olefins with nitriles was successfully achieved. Various aliphatic, cyclic, and aromatic olefins, and various aliphatic and aromatic nitriles were used in this reaction to give secondary amides in high yields.
Graphical abstractNbCl5-mediated amidation of olefins with nitriles was successfully achieved to give secondary amides in high yields.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Kaoru Yasuda, Yasushi Obora,