Phospha-Michael addition of phosphorus nucleophiles to α,β-unsaturated malonates using 3-aminopropylated silica gel as an efficient and recyclable catalyst

3-Aminopropylated silica gel, which is prepared from commercially available and cheap starting materials, is introduced as an efficient and recyclable catalyst for the phospha-Michael addition of phosphorus nucleophiles to α,β-unsaturated malonates. Short reaction times, mild reaction conditions, ease of recovery and catalyst reusability make this method a new, economic and waste-free chemical process for the synthesis of β-phosphonomalonates.

Graphical abstract3-Aminopropylated silica gel, is introduced as an efficient and recyclable catalyst for the phospha-Michael addition of phosphorus nucleophiles to α,β-unsaturated malonates. Short reaction times, mild reaction conditions, ease of recovery and catalyst reusability make this method a new, economic and waste-free chemical process for the synthesis of β-phosphonomalonates.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► β-Phosphono malonates were synthesized by phospha-Michael addition reaction. ► Phospha-Michael addition reaction was efficiently catalyzed by 3-aminopropylated silica gel. ► Different phosphite esters reacted with α,β-unsaturated malonates.