A recyclable and highly effective sulfated TiO2-P25 for the synthesis of quinoxaline and dipyridophenazine derivatives at room temperature

Sulfated TiO2-P25 has been prepared using H2SO4 and used for the synthesis of quinoxaline and dipyridophenazine derivatives. Sulfate loading by H2SO4 increases the Lewis acidity of TiO2-P25. This catalyst gives excellent yield with less reaction time and it is an inexpensive, easily recyclable catalyst for this reaction.

Graphical abstractBiologically active quinoxalines and dipyridophenazines were efficiently synthesized in excellent yield and less reaction time using inexpensive, easily recyclable TiO2-P25-SO42−. Synthesis of quinoxalines with this catalyst can also be carried out in water.Figure optionsDownload full-size imageDownload as PowerPoint slide