Palladium-catalyzed C–H bond functionalization/oxidative acyloxylation of 2-aryl-benzo[d]thiazoles

•2-Arylbenzo[d]thiazole-assisted ortho-acyloxylation has described.•CAr–O bond formation proceeded efficiently.•Wide substrate scope with good functional group tolerance has been demonstrated.•Proposed mechanism for the ortho-acyloxylation reaction is depicted.

A chelation-assisted Pd-catalyzed ortho-acyloxylation reaction of the 2-arylbenzo[d]thiazole is described via sp2 C–H bond activation. A wide substrate scope with good functional group tolerance has been demonstrated, affording mono- or diacyloxylation products in moderate to good yields. This method is an alternative route for the preparation of 2-arylbenzo[d]thiazole derivatives via a C–H activation mechanism.

Graphical abstractA chelation-assisted Pd-catalyzed ortho-acyloxylation reaction of the 2-arylbenzo[d]thiazole is described via sp2 C–H bond activation. A wide substrate scope with good functional group tolerance has been demonstrated, affording mono- or diacyloxylated products in moderate to good yields.Figure optionsDownload full-size imageDownload as PowerPoint slide