| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1322717 | Journal of Organometallic Chemistry | 2010 | 4 Pages |
(2-Fluoro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1a) and (2-chloro-5-pyridyl)dimethyl(oxiran-2-ylmethyl)silane (1b) were prepared in two-step syntheses, starting from allylchlorodimethylsilane. Compounds 1a and 1b were characterized by elemental analyses and NMR studies. With the synthesis of 1a and 1b, new potential building blocks for the synthesis of silicon-containing drugs have been made accessible.
Graphical abstractThe (2-halogeno-5-pyridyl)dimethyl(oxiran-2-ylmethyl)-silanes 1a and 1b were prepared in two-step syntheses, starting from allylchlorodimethylsilane. Compounds 1a and 1b were characterized by elemental analyses and NMR studies. With the synthesis of compounds 1a and 1b, new potential building blocks for the synthesis of silicon-containing drugs have been made accessible.Figure optionsDownload full-size imageDownload as PowerPoint slide
