Article ID Journal Published Year Pages File Type
1323768 Journal of Organometallic Chemistry 2006 10 Pages PDF
Abstract

Total Synthesis of (±)-erythrocarine was achieved using ruthenium-catalyzed dienyne metathesis as a key step. A tetrahydroisoquinoline skeleton having tetrasubstituted carbon center was constructed using our method, that is, carbon dioxide and an alkyl group were introduced onto an alkyne having a heteroatom in a tether using the nickel complex to produce α,β-unsaturated carboxylic acid and then isoquinoline skeleton was constructed by Michael reaction of the tethered nitrogen to the resultant α,β-unsaturated ester.

Graphical abstractTotal Synthesis of (±)-erythrocarine was achieved using ruthenium-catalyzed dienyne metathesis as a key step.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
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