| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1323922 | Journal of Organometallic Chemistry | 2006 | 6 Pages |
Resolution of the atropisomeric chiral BIPHEP ligand on Rh has been achieved with the aid of 2-(4-tert-butyl-phenyl)-8-methoxy-1,8-dimethyl-bicyclo[2.2.2]octa-2,5-diene, a chiral chelating diene ligand. The diene complex 3 containing an (S)-BIPHEP ligand was found to be configurationally stable in CDCl3 solution at RT. Conversion of the diene complex 3 to a dicarbonyl Rh complex 4 that had a barrier of 25.0 kcal/mol for atropisomerization of the BIPHEP ligand. Preliminary studies of the use of the resolved complex 3 for catalysis are presented.
Graphical abstractResolution of the atropisomerically chiral BIPHEP ligand on Rh has been achieved with the aid of a chiral diene ligand. The diene complex containing an (S)-BIPHEP ligand was found to be configurationally stable in CDCl3 solution at RT. Conversion of the diene complex to a dicarbonyl Rh complex that had a barrier of 25.0 kcal/mol for atropisomerization of the BIPHEP ligand.Figure optionsDownload full-size imageDownload as PowerPoint slide
