Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1324861 | Journal of Organometallic Chemistry | 2011 | 5 Pages |
The group’s recent advances in catalytic carbon-to-heteroatom bond forming reactions of alkenes and alkynes are described. For the C–O bond formation reaction, a well-defined bifunctional ruthenium-amido catalyst has been successfully employed for the conjugate addition of alcohols to acrylic compounds. The ruthenium-hydride complex (PCy3)2(CO)RuHCl was found to be a highly effective catalyst for the regioselective alkyne-to-carboxylic acid coupling reaction in yielding synthetically useful enol ester products. Cationic ruthenium-hydride catalyst generated in-situ from (PCy3)2(CO)RuHCl/HBF4·OEt2 was successfully utilized for both the hydroamination and related C–N bond forming reactions of alkenes. For the C–Si bond formation reaction, regio- and stereoselective dehydrosilylation of alkenes and hydrosilylation of alkynes have been developed by using a well-defined ruthenium-hydride catalyst. Scope and mechanistic aspects of these carbon-to-heteroatom bond forming reactions are discussed.
Graphical abstractRecent advances in ruthenium-catalyzed C–X bond formation reactions are described. Regio- and stereoselective addition of alcohols, amines and silanes to alkenes and alkynes have been achieved by using well-defined ruthenium-hydride catalysts. Scope and mechanistic analyses of these reactions are delineated.Figure optionsDownload full-size imageDownload as PowerPoint slide