Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1324877 | Journal of Organometallic Chemistry | 2011 | 7 Pages |
A catalytic system consisting of [Ni(cod)2] and ligand dppf enabled an efficient synthesis of differently substituted indoles through a modular reaction sequence, which consists of intermolecular aminations and intramolecular hydroaminations with ortho-alkynylhaloarenes.
Graphical abstractA catalytic system consisting of [Ni(cod)2] and ligand dppf enabled an efficient synthesis of differently substituted indoles through a modular reaction sequence, which consists of intermolecular aminations and intramolecular hydroaminations with ortho-alkynylhaloarenes.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch Highlights► Nickel-catalyzed intermolecular aminations of aryl halides. ► Intramolecular hydroamination of alkynes. ► Aryl- and alkyl-substituted amines are viable substrates.