| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1324890 | Journal of Organometallic Chemistry | 2011 | 5 Pages |
Enantioselective intramolecular hydroamination of N-allenyl ureas catalyzed by an enantiomerically enriched bis(gold) phosphine complex forms pyrrolidine derivatives in good yield with up to 93% ee.
Graphical abstractEnantioselective intramolecular hydroamination of N-γ-allenyl ureas catalyzed by an enantiomerically enriched bis(gold) phosphine complex forms pyrrolidine derivatives in good yield with up to 93% ee.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► Bis(gold) phosphine complex catalyzes the enantioselective hydroamination of N-allenyl ureas. ► Enantioselectivities of up to 93% ee were obtained. ► Enantioselectivity depended strongly on backbone substitution. ► Axially chiral allenes underwent hydroamination via a catalyst-controlled pathway.
