Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1324904 | Journal of Organometallic Chemistry | 2011 | 14 Pages |
This review focuses mainly on recent endeavors in the field of cyclizations triggered by the catalytic hydroamination (formal or direct) of alkynes. The new strategies developed offer an efficient and convenient entry to several heterocycles of biological importance.
Graphical abstractThis review focuses mainly on recent endeavors in the field of cyclizations triggered by the catalytic hydroamination (formal or direct) of alkynes. The new strategies developed offer an efficient and convenient entry to several heterocycles of biological importance.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch highlights► Alkyne hydroamination triggered cyclizations represents a powerful method in organic synthesis. ► An efficient synthesis of biological important heterocycles could be achieved using alkyne hydroamination initiated processes. ► There is a need exists for developing enantioselective methods. ► Only one report exists on ammonia as hydroamination partner for reaction with alkynes.