| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1325255 | Journal of Organometallic Chemistry | 2009 | 5 Pages |
The first conjugates of closo-dodecaborate anion with nucleoside-thymidine were synthesized. The nucleophilic cleavage of dioxonium derivative of closo-dodecaborate by 3′,5′-bis(t-butyldimethylsilyl)-thymidine and “click” reaction between B12-based azide and 3N-(4-pentyn-1-yl)thymidine were appeared as convenient approaches towards the synthesis of this new class of nucleoside-based boron cluster conjugates.
Graphical abstractThe first conjugates of closo-dodecaborate anion with nucleoside-thymidine were synthesized. The nucleophilic cleavage of dioxonium derivative of closo-dodecaborate by 3′,5′-bis(t-butyldimethylsilyl)-thymidine and “click” reaction between B12-based azide and 3N-(4-pentyn-1-yl)thymidine were appeared as convenient approaches towards the synthesis of this new class of nucleoside-based boron cluster conjugates.Figure optionsDownload full-size imageDownload as PowerPoint slide
