| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1325429 | Journal of Organometallic Chemistry | 2009 | 4 Pages |
A series of silver complexes generated in situ from AgOSO2CF3 (AgOTf) and a range of bidentate ligands were investigated as catalysts for the intramolecular hydroamination of 4-pentyn-1-amine. A variety of P- and N-donor ligands were tested including the novel pyrazole-phosphine ligand 1-(2-(diphenylphosphino)phenyl)pyrazole. The best catalyst was formed from equimolar amounts of the P,N-donor ligand 1-(2-(diphenylphosphino)ethyl)pyrazole and AgOTf, which achieved a turnover rate of 129 h−1 for the cyclisation of 4-pentyn-1-amine.
Graphical abstractSilver complexes generated in situ from AgOTf and a series of bidentate P- and N-donor ligands, including the novel pyrazole-phosphine ligand 1-(2-(diphenylphosphino)phenyl)pyrazole, were investigated as catalysts for the intramolecular hydroamination of 4-pentyn-1-amine. The best catalyst (turnover rate = 129 h−1) was formed from equimolar ammounts of 1-(2-(diphenylphosphino)ethyl)pyrazole and AgOTf.Figure optionsDownload full-size imageDownload as PowerPoint slide
