Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1325554 | Journal of Organometallic Chemistry | 2014 | 5 Pages |
•Synthesis of ferrocene derivatives functionalized with α-methylene-γ-butyrolactone rings.•α-Methylene-γ-butyrolactones are versatile structural units present in various important natural products.•Reformatsky-type reaction applied in the synthesis of organometallic compounds.
This work reports the synthesis and characterization of new ferrocene derivatives functionalized with one or two α-methylene-γ-butyrolactone rings. These compounds were prepared via Reformatsky-type reaction between carbonyl ferrocene derivatives and ethyl 2-bromomethylacrylate in 33–85% yields.
Graphical abstractThis work reports the synthesis of new ferrocene derivatives functionalized with one or two α-methylene-γ-butyrolactone rings by reformatsky-type reaction.Figure optionsDownload full-size imageDownload as PowerPoint slide