Structure and reactivity of bis(iodozincio)methane solution

Bis(iodozincio)methane, which has been shown to be an efficient reagent for organic synthesis, is obtained as THF solution. The structural information about the reagent as THF solution was corrected by small angle neutron scattering and by anomalous X-ray scattering. Those scattering experiments implied that the prepared bis(iodozincio)methane exists without forming any oligomer or aggregate. A coordination of tetrahydrothiophene to bis(iodozincio)methane enhances the nucleophilicity of the reagent and stabilizes its monomeric structure in the solution.

Graphical abstractThe structural information about bis(iodozincio)methane as THF solution was corrected by small angle neutron scattering and by anomalous X-ray scattering. Those scattering experiments implied that the prepared bis(iodozincio)methane exists without forming any oligomer or aggregate.Figure optionsDownload full-size imageDownload as PowerPoint slide