Stereoselective [3+2+2] cycloaddition utilizing optically active binuclear Fischer carbene complexes with alkynes

The reaction of optically active α,β-unsaturated binuclear Fischer carbene complexes with alkynes gave planar chiral cycloheptatriene chromium complexes via [3+2+2] cycloaddition with high diastereoselectivity.

Graphical abstractStereoselective [3+2+2] cycloaddition reaction of optically active binuclear α,β-unsaturated Fischer carbene complexes with alkynes via nickel carbene complexes gave planar chiral cycloheptatriene chromium complexes with high diastereoselectivity. The chromium-coordinated both rings of the product were stereo- and chemoselectively functionalized by utilizing distinct properties of the chromium complex.Figure optionsDownload full-size imageDownload as PowerPoint slide