Rhodium-catalyzed hydroformylation of olefins: Effect of [bis(2,4-di-tert-butyl) pentaerythritol] diphosphite (alkanox P-24) on the regioselectivity of the reaction

Rhodium (I) associated with [bis(2,4-di-tert-butyl) pentaerythritol] diphosphite (I) as a ligand represents an active catalyst system for highly regioselective hydroformylation of various alkenes. The commercially available bis(2,4-di-tert-butyl)pentaerythritol diphosphite (alkanox P-24) (I), which has been used so far as an antioxidant in the stabilization of polymers, was used as a diphosphite ligand for the selective hydroformylation reaction of olefins. Excellent selectivity towards linear aldehydes and excellent conversions were achieved in the hydroformylation of alkenes. The hydroformylation reaction was applied to various olefinic substrates including the internal alkenes.

Graphical abstractRhodium (I) with [bis(2,4-di-tert-butyl) pentaerythritol] diphosphite (I) as a ligand represents an active catalysts system for highly regioselective hydroformylation of various alkenes. Excellent ratios (19 and 24) of linear to branched aldehydes were obtained with the hydroformylation of 1-octene. The reaction was applied to various olefinic substrates including the internal alkenes.Figure optionsDownload full-size imageDownload as PowerPoint slide