Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1326852 | Journal of Organometallic Chemistry | 2007 | 5 Pages |
Abstract
A pharmacokinetics study of antileukaemic melarsoprol and arsthinol has been done. In the bone marrow, arsenic concentrations were very high, especially that of melarsoprol. The brain concentrations were high, although lower than in the bone marrow. This fact is in accordance with the antileukaemic activity and the brain toxicity of these organoarsenicals.
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Siham Ben Zirar, Stéphane Gibaud, Alexandra Camut, Alain Astier,